Providing novel and effective devices in order to make structures stable under unpredicted natural loads has become a challenging issue for civil engineers. Tuned mass damper (TMD) is one of the effective methods to make structures resistant against the natural dynamic loads such as earthquake and wind. In this paper, the influence of single tuned mass damper (STMD) and multiple tuned mass dampers (MTMDs) on the settling time of tall steel building under seismic loads was evaluated. For this aim, one lumped-mass structure with 20 stories was modelled. The mass ratio, damping ratio and the stiffness of dampers were the variables considered in this study. To model the structure, SAP2000 software was employed. Then, time history analysis scheme was carried out to assess the performance of structure. The obtained outcomes indicated that the displacement of structure strongly depends on the earthquake record. Moreover, the displacement was substantially reduced by using an appropriate TMDs distribution. Generally, TMD has activated after a first maximum applied load amplitude and will become able to reduce subsequent amplitudes. So, it should be stated that the structural responses of the building could be considerably reduced by providing the effective MTMDs in different stories and regulate the characteristics of dampers based on the structural parameters of tall buildings.